Selective ther cleavage in the aporphine series. Conversion of (S)-bulbocapnine into (S)-corytuberine and (S)-corydine methyl ether.

@article{Gerecke1976SelectiveTC,
  title={Selective ther cleavage in the aporphine series. Conversion of (S)-bulbocapnine into (S)-corytuberine and (S)-corydine methyl ether.},
  author={Max Gerecke and Ren{\'e} Borer and Arnold Brossi},
  journal={Helvetica chimica acta},
  year={1976},
  volume={59 7},
  pages={
          2551-7
        }
}
Bulbocapnine methyl ether (2), on treatment with boron halides, affords the aporphine-1,2-diol (3), the novel aporphines 5 and 6 or the phenanthrene derivative 11 depending on the reaction conditions. 3 can be further transformed into corydine methyl ether (4); 6 has been converted to corytuberine (8). Similarly, dehydrobulbocapnine methyl ether 9 was converted to 10. 
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References

SHOWING 1-3 OF 3 REFERENCES
Entfernung von Alkohol aus Chloroform
Fur die Herstellung stabilisatorfreien Chloroforms wird eine neue Methode beschrieben, die auf adsorptiver Filtration an hochaktivem Aluminiumoxyd beruht und sich schnell und bequem anwenden last.