Selective subcellular localization of cations with variants of the potassium (pyro)antimonate technique.

@article{Simson1975SelectiveSL,
  title={Selective subcellular localization of cations with variants of the potassium (pyro)antimonate technique.},
  author={John Simson and Samuel S. Spicer},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={1975},
  volume={23 8},
  pages={575-98}
}
Fixation of rat parotid with an unbuffered osmium tetroxide solution containing nearly saturated potassium (pyro)antimonate resulted in abundant deposition of cation-antimonate precipatates in acinar cells. Altering the antimonate concentration, including buffers or chelators in the solution or changing the primary fixative resulted in an altered intensity and distribution of the precipitates formed in the tissue, apparently reflecting a degree of selectivity in ion localization. Decreasing the… CONTINUE READING
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