Selective species specificity of tumor necrosis factor for toxicity in the mouse.

@article{Brouckaert1992SelectiveSS,
  title={Selective species specificity of tumor necrosis factor for toxicity in the mouse.},
  author={P. G. G. Brouckaert and Claude Libert and Bart Everaerdt and Walter Fiers},
  journal={Lymphokine and cytokine research},
  year={1992},
  volume={11 4},
  pages={193-6}
}
The selective cytotoxic activity of tumor necrosis factor (TNF) on many transformed human or murine cell lines is (almost) not species-specific. There are, however, a limited number of biological assay systems such as gene induction in murine thymoma cells and the murine thymocyte proliferation assay, in which recombinant murine (rm) TNF, but not recombinant human (rh) TNF is active. We have now investigated the possible species specificity of the lethality-inducing properties of TNF in the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Effects of cytokines and infections on brain neurochemistry

Clinical Neuroscience Research • 2006
View 2 Excerpts

Limb salvage with isolated perfusion for soft tissue sarcoma: could less TNF-alpha be better?

Annals of oncology : official journal of the European Society for Medical Oncology • 2005
View 1 Excerpt

Similar Papers

Loading similar papers…