Selective retention of essential fatty acids: the role of hepatic monoacylglycerol acyltransferase.

@article{Xia1993SelectiveRO,
  title={Selective retention of essential fatty acids: the role of hepatic monoacylglycerol acyltransferase.},
  author={Tao Xia and Nadia A. Mostafa and Balasubramany Bhat and Gregory L. Florant and Rosalind A Coleman},
  journal={The American journal of physiology},
  year={1993},
  volume={265 2 Pt 2},
  pages={R414-9}
}
In the suckling rat, chick embryo, and hibernating marmot, fatty acids provide the major source of energy, and despite the high rate of hepatic beta-oxidation, these animals selectively retain long-chain polyunsaturated derivatives of C18:2n-6 and C18:3n-3. To determine whether the hepatic microsomal activity monoacylglycerol acyltransferase (MGAT) (EC 2.3.1.22) could provide a mechanism to selectively acylate monoacylglycerols that contain essential fatty acids, we tested the ability of MGAT… CONTINUE READING