Selective resistance of LDL core lipids to iron-mediated oxidation. Implications for the biological properties of iron-oxidized LDL.

@article{Tribble1996SelectiveRO,
  title={Selective resistance of LDL core lipids to iron-mediated oxidation. Implications for the biological properties of iron-oxidized LDL.},
  author={Diane L. Tribble and Berbie M. Chu and Gerri A. Levine and Ronald M. Krauss and E. L. Gong},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={1996},
  volume={16 12},
  pages={1580-7}
}
Although the nature and consequences of oxidative changes in the chemical constituents of low density lipoproteins (LDLs) have been extensively examined, the physical dynamics of LDL oxidation and the influence of physical organization on the biological effects of oxidized LDLs have remained relatively unexplored. To address these issues, in the present studies we monitored surface- and core-specific peroxidative stress relative to temporal changes in conjugated dienes (CDs), particle charge… CONTINUE READING