Selective removal of lateral olivocochlear efferents increases vulnerability to acute acoustic injury.

@article{Darrow2007SelectiveRO,
  title={Selective removal of lateral olivocochlear efferents increases vulnerability to acute acoustic injury.},
  author={Keith N Darrow and St{\'e}phane F Maison},
  journal={Journal of neurophysiology},
  year={2007},
  volume={97 2},
  pages={
          1775-85
        }
}
Cochlear sensory cells and neurons receive efferent feedback from the olivocochlear (OC) system. The myelinated medial component of the OC system and its effects on outer hair cells (OHCs) have been implicated in protection from acoustic injury. The unmyelinated lateral (L)OC fibers target ipsilateral cochlear nerve dendrites and pharmacological studies suggest the LOC's dopaminergic component may protect these dendrites from excitotoxic effects of acoustic overexposure. Here, we explore LOC… CONTINUE READING
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