Selective removal of apolipoprotein B-containing serum lipoproteins from blood plasma.

  title={Selective removal of apolipoprotein B-containing serum lipoproteins from blood plasma.},
  author={W. Stoffel and Thomas Demant},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={78 1},
Studies were undertaken to determine the applicability and effectiveness of immunoadsorption chromatography on anti-low density lipoprotein (LDL) columns as a plasma-cholesterol-lowering procedure. Mass production and isolation of monospecific antibodies against swine LDL (rho = 1.006-1.063 g/ml) was carried out by immunization of sheep with swine LDL and selective antibody adsorption from their antisera by chromatography on LDL-Sepharose. The isolated LDL antibodies were then covalently linked… CONTINUE READING
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Publications referenced by this paper.

Biochemistry 14 , 2817 - 2823

  • M. Miller-Andersson, H. Borg
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  • 1975