Selective regimen shift and demographic growth increase associated with the emergence of high-fitness variants of canine parvovirus.

@article{Pereira2007SelectiveRS,
  title={Selective regimen shift and demographic growth increase associated with the emergence of high-fitness variants of canine parvovirus.},
  author={C{\'e}sar Augusto Din{\'o}la Pereira and Elcio S Leal and Edison Luiz Durigon},
  journal={Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases},
  year={2007},
  volume={7 3},
  pages={
          399-409
        }
}
The natural evolution of Canine parvovirus (CPV) is characterized by a variety of mutations, mainly in the VP1/VP2 gene. Although positive selection has been previously reported in CPV, little is known about its overall contribution to viral adaptation in the canine population. Herein, the influences of the evolutive constraints on CPV during a period of viral adaptation into a previously uninfected population are more clearly investigated. To do this, 31 sequences of VP1/VP2 gene obtained from… CONTINUE READING
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