Selective reductions in subpopulations of GABAergic neurons in a developmental rat model of epilepsy.

@article{Gill2010SelectiveRI,
  title={Selective reductions in subpopulations of GABAergic neurons in a developmental rat model of epilepsy.},
  author={Daphne A Gill and Sarah L Ramsay and R Andrew Tasker},
  journal={Brain research},
  year={2010},
  volume={1331},
  pages={114-23}
}
In the rat, early postnatal development is a critical period for neuronal migration, differentiation and network formation, requiring appropriate and timely glutamate and gamma-aminobutyric acid (GABA) signaling. Insults that affect either of these systems may result in increased excitatory activity, potentially leading to changes in neuronal proliferation and/or connectivity. We have previously shown that postnatal administration of low doses of domoic acid (DOM) can produce many of the… CONTINUE READING

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