Selective reduction of excitatory hippocampal sharp waves by docosahexaenoic acid and its methyl ester analog ex-vivo.

Abstract

Excitatory sharp waves (SPWs) originating from the hippocampus are considered to model the interictal "spikes" that occur in people with temporal lobe epilepsy. Docosahexaenoic acid (DHA) is an omega-3 polyunsaturated fatty acid that has been reported to reduce neuronal excitability in vitro. The effect of DHA on hippocampal SPWs, however, is not known. Our… (More)
DOI: 10.1016/j.brainres.2013.09.004

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Cite this paper

@article{Taha2013SelectiveRO, title={Selective reduction of excitatory hippocampal sharp waves by docosahexaenoic acid and its methyl ester analog ex-vivo.}, author={Ameer Y Taha and Tariq Zahid and Tina M Epps and M O Tr{\'e}panier and W. McIntyre Burnham and Richard P. Bazinet and Liang Zhang}, journal={Brain research}, year={2013}, volume={1537}, pages={9-17} }