Selective recruitment of non-classical monocytes promotes skeletal muscle repair.

  title={Selective recruitment of non-classical monocytes promotes skeletal muscle repair.},
  author={Cheryl L San Emeterio and Claire E Olingy and Yihsuan Chu and Edward A. Botchwey},
Regeneration of traumatic defects in skeletal muscle requires the synchronized behavior of multiple cells that participate in repair. The inflammatory cascade that is rapidly initiated after injury serves as a powerful node at which to guide the progression of healing and influence tissue repair. Here, we examine the role that myeloid cells play in the healing of traumatic skeletal muscle injury, and leverage their pro-regenerative functions using local delivery of the immunomodulatory small… CONTINUE READING
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