Selective protection from the inhibition by EEDQ of D1 and D2 dopamine agonist-induced rotational behavior in mice.

Abstract

Mice with unilateral lesions of dopamine nigrostriatal neurons produced by injecting 6-hydroxydopamine into the striatum exhibited contralateral rotational behavior to the non-selective dopamine agonist apomorphine, the D1 dopamine agonist SKF 38393, and the D2 agonist quinpirole. The non-specific dopamine antagonist EEDQ blocked the circling responses to… (More)

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Cite this paper

@article{Goodale1988SelectivePF, title={Selective protection from the inhibition by EEDQ of D1 and D2 dopamine agonist-induced rotational behavior in mice.}, author={David B. Goodale and Assaf Jacobi and D. G. Chandler J. P. McNamara M. M. Gribb M. S. Seyfried and B. Weiss}, journal={Pharmacology, biochemistry, and behavior}, year={1988}, volume={30 2}, pages={457-62} }