Selective progesterone receptor modulators (SPRMs): progesterone receptor action, mode of action on the endometrium and treatment options in gynecological therapies

@inproceedings{Wagenfeld2016SelectivePR,
  title={Selective progesterone receptor modulators (SPRMs): progesterone receptor action, mode of action on the endometrium and treatment options in gynecological therapies},
  author={Andrea Wagenfeld and Philippa T K Saunders and Lucy H. R. Whitaker and Hilary O D Critchley},
  booktitle={Expert opinion on therapeutic targets},
  year={2016}
}
INTRODUCTION The progesterone receptor plays an essential role in uterine physiology and reproduction. Selective progesterone receptor modulators (SPRMs) have emerged as a valuable treatment option for hormone dependent conditions like uterine fibroids, which have a major impact on women's quality of life. SPRMs offer potential for longer term medical treatment and thereby patients may avoid surgical intervention. AREAS COVERED The authors have reviewed the functional role of the progesterone… CONTINUE READING
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