Selective presynaptic insectotoxin (alpha-latroinsectotoxin) isolated from black widow spider venom.

@article{Magazanik1992SelectivePI,
  title={Selective presynaptic insectotoxin (alpha-latroinsectotoxin) isolated from black widow spider venom.},
  author={Lev G Magazanik and Irina M. Fedorova and Galina Kovalevskaya and V. N. Pashkov and Oleg V Bulgakov and Eugene V. Grishin},
  journal={Neuroscience},
  year={1992},
  volume={46 1},
  pages={181-8}
}
A homogenous protein of 120,000 mol. wt isolated from black widow spider (Lactrodectus mactans tredecimguttatus) venom and referred to as alpha-latroinsectotoxin was highly potent (4 nM) in the induction of an increase of the frequency of miniature excitatory postsynaptic potentials in blowfly (Calliphora vicina) larvae neuromuscular preparations. In the… CONTINUE READING