Selective pressure-regulated retroinfusion of fibroblast growth factor-2 into the coronary vein enhances regional myocardial blood flow and function in pigs with chronic myocardial ischemia.

@article{Degenfeld2003SelectivePR,
  title={Selective pressure-regulated retroinfusion of fibroblast growth factor-2 into the coronary vein enhances regional myocardial blood flow and function in pigs with chronic myocardial ischemia.},
  author={Georges von Degenfeld and Philip W.J. Raake and Christian Kupatt and Corinna Lebherz and Rabea Hinkel and Franz Josef Gildehaus and Wolfgang Muenzing and Andrea Kranz and Johannes Waltenberger and Marcus Thadeu Ven{\~a}ncio Simōes and Markus Schwaiger and E. Thein and Peter Boekstegers},
  journal={Journal of the American College of Cardiology},
  year={2003},
  volume={42 6},
  pages={1120-8}
}
OBJECTIVES We sought to improve regional myocardial delivery and subsequent collateral perfusion induced by basic fibroblast growth factor-2 (FGF-2) using selective pressure-regulated retroinfusion of coronary veins for delivery. This hypothesis was tested in a newly developed pig model with percutaneous induction of chronic ischemia. BACKGROUND Selective pressure-regulated retroinfusion of coronary veins is a catheter-based procedure that has been shown to provide effective regional delivery… CONTINUE READING

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