Selective potentiation of peripheral chemoreflex sensitivity in obstructive sleep apnea.

@article{Narkiewicz1999SelectivePO,
  title={Selective potentiation of peripheral chemoreflex sensitivity in obstructive sleep apnea.},
  author={Krzysztof Narkiewicz and Philippe van de Borne and C A Pesek and Mark Eric Dyken and N. Montano and V. K. Somers},
  journal={Circulation},
  year={1999},
  volume={99 9},
  pages={1183-9}
}
BACKGROUND The chemoreflexes are an important mechanism for regulation of both breathing and autonomic cardiovascular function. Abnormalities in chemoreflex mechanisms may be implicated in increased cardiovascular stress in patients with obstructive sleep apnea (OSA). We tested the hypothesis that chemoreflex function is altered in patients with OSA. METHODS AND RESULTS We compared ventilatory, sympathetic, heart rate, and blood pressure responses to hypoxia, hypercapnia, and the cold pressor… CONTINUE READING
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Sympathetic neural responses to transient hypoxia are increased in obstructive sleep apnea.Circulation. 1996;94(suppl I):I-544

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