Selective photodynamic therapy based on aggregation-induced emission enhancement of fluorescent organic nanoparticles.

@article{Chang2012SelectivePT,
  title={Selective photodynamic therapy based on aggregation-induced emission enhancement of fluorescent organic nanoparticles.},
  author={Cheng-Chung Chang and Meng-Chieh Hsieh and Jung-Chih Lin and Ta-Chau Chang},
  journal={Biomaterials},
  year={2012},
  volume={33 3},
  pages={897-906}
}
Three binary molecule conjugates were designed and synthesized by conjugating a chromophore (3, 6-bis-(1-methyl-4-vinylpyridinium)-carbazole diiodide, BMVC) to mono-, bis- and trishydroxyl photosensitizers, respectively. BMVC plays the role of cancer cells recognizer; AIEE (aggregation-induced emission enhancement) generator and FRET (Fluorescence Resonance… CONTINUE READING