Selective neurotoxicity of ruthenium red in primary cultures

Abstract

The inorganic dye ruthenium red (RuR) has been shown to be neurotoxic in vivo when injected intracerebrally. In this work toxicity of RuR was compared in primary cultures of rat cotical neurons, cerebellar granule neurons and cerebellar astroglia. Microscopic examination of the cultures revealed that RuR penetrates the somata of both types of neurosn used… (More)
DOI: 10.1007/BF01694542

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