Selective neurofilament (SMI-32, FNP-7 and N200) expression in subpopulations of layer V pyramidal neurons in vivo and in vitro.

@article{Voelker2004SelectiveN,
  title={Selective neurofilament (SMI-32, FNP-7 and N200) expression in subpopulations of layer V pyramidal neurons in vivo and in vitro.},
  author={Courtney C. J. Voelker and Nathalie Garin and Jeremy S H Taylor and Beat H. G{\"a}hwiler and J. -P. Hornung and Zolt{\'a}n Moln{\'a}r},
  journal={Cerebral cortex},
  year={2004},
  volume={14 11},
  pages={
          1276-86
        }
}
There are two main types of layer V pyramidal neurons in rat cortex. Type I neurons have tufted apical dendrites extending into layer I, produce bursts of action potentials and project to subcortical targets (spinal cord, superior colliculus and pontine nuclei). Type II neurons have apical dendrites, which arborize in layers II-IV, do not produce bursts of action potentials and project to ipsilateral and contralateral cortex. The specific expression of different genes and proteins in these two… CONTINUE READING

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