Selective muscarinic antagonists as bronchodilators.

  title={Selective muscarinic antagonists as bronchodilators.},
  author={Henri N. Doods},
  journal={Agents and actions. Supplements},
The non-selective muscarinic antagonist ipratropium is widely used as bronchodilator. Due to its pharmacokinetic properties this drug, after inhalation, acts only locally on the airways and no unwanted anticholinergic side-effects are observed. Another approach is the use of selective muscarinic antagonists. Based on their selectivity for M3- and/or M1… CONTINUE READING