Selective maximization of (31)P MR spectroscopic signals of in vivo human brain metabolites at 3T.

@article{Blenman2007SelectiveMO,
  title={Selective maximization of (31)P MR spectroscopic signals of in vivo human brain metabolites at 3T.},
  author={Rose-Ann M Blenman and John D Port and Joel P. Felmlee},
  journal={Journal of magnetic resonance imaging : JMRI},
  year={2007},
  volume={25 3},
  pages={628-34}
}
PURPOSE To develop a short TR, short TE, large flip angle (LFA), in vivo (31)P MR spectroscopy (MRS) technique at 3T that selectively maximizes the signal-to-noise ratio (SNR) of long T(1) human brain metabolites implicated in bipolar disorder. MATERIALS AND METHODS Two pulse sequences were evaluated for efficiency. Slice profiles acquired with the scaled, sinc-shaped, radiofrequency (RF) LFA pulses were compared to those acquired with Shinnar-Le Roux (SLR) RF LFA pulses. The SLR-based LFA… CONTINUE READING