Selective localization of Bcl-2 to the inner mitochondrial and smooth endoplasmic reticulum membranes in mammalian cells

Abstract

Bcl-2, an anti-apoptotic protein, is believed to be localized in the outer mitochondrial membrane, endoplasmic reticulum, and nuclear envelope. However, Bcl-2 has also been suggested as playing a role in the maintenance of mitochondrial membrane potential, indicating its possible association with the inner mitochondrial membrane. We therefore further… (More)
DOI: 10.1038/sj.cdd.4400694

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Cite this paper

@article{Gotow2000SelectiveLO, title={Selective localization of Bcl-2 to the inner mitochondrial and smooth endoplasmic reticulum membranes in mammalian cells}, author={Tsukasa Gotow and M. Shibata and Satoru Kanamori and Osamu Tokuno and Y. Ohsawa and N. Sato and Kyoko Isahara and Y Yayoi and T. Watanabe and Jean François Leterrier and M. Linden and Eiji Kominami and Yuri Uchiyama}, journal={Cell Death and Differentiation}, year={2000}, volume={7}, pages={666-674} }