Selective inhibition of endothelium-dependent relaxation by sympathectomy in rabbit carotid artery rings in vitro.

@article{Kars1993SelectiveIO,
  title={Selective inhibition of endothelium-dependent relaxation by sympathectomy in rabbit carotid artery rings in vitro.},
  author={Hamit Zafer Kars and Tijen Utkan and Yusuf Sarioğlu and V Yaradanakul},
  journal={Methods and findings in experimental and clinical pharmacology},
  year={1993},
  volume={15 1},
  pages={35-40}
}
The influence of cervical and periarterial sympathectomy on endothelium-dependent relaxation of the rabbit common carotid artery was studied in vitro. Noradrenaline, serotonin, acetylcholine and papaverine concentration-response curves of sympathectomized and control rabbit common carotid artery rings were recorded and analyzed and effects of endothelium removal were investigated. Endothelium-dependent relaxation was selectively and significantly inhibited in 3 weeks postsympathectomy arterial… CONTINUE READING