Selective inhibition of a slow-inactivating voltage-dependent K+ channel in rat PC12 cells by hypoxia.

@article{Conforti1997SelectiveIO,
  title={Selective inhibition of a slow-inactivating voltage-dependent K+ channel in rat PC12 cells by hypoxia.},
  author={Laura Conforti and David E. Millhorn},
  journal={The Journal of physiology},
  year={1997},
  volume={502 ( Pt 2)},
  pages={293-305}
}
1. Electrophysiological (single-channel patch clamp) and molecular biological experiments (reverse transcriptase-polymerase chain reaction) were performed to attempt to identify the O2-sensitive K+ channel in rat phaeochromocytoma (PC12) cells. 2. Four types of K+ channels were recorded in PC12 cells: a small-conductance K+ channel (14 pS), a calcium-activated K+ channel (KCa; 102 pS) and two K+ channels with similar conductance (20 pS). These last two channels differed in their time-dependent… CONTINUE READING

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