Selective induction of stalk-cell-specific proteins in Dictyostelium.

  title={Selective induction of stalk-cell-specific proteins in Dictyostelium.},
  author={Will Kopachik and B. Dhokia and Robert R Kay},
  journal={Differentiation; research in biological diversity},
  volume={28 3},
We compared the proteins synthesized and accumulated by Dictyostelium discoideum amoebae in response to the morphogenetic factor termed differentiation-inducing factor (DIF) to assess the proposed ability of DIF to regulate the choice of differentiation pathway. When amoebae of a mutant strain with low endogenous DIF levels were given DIF, they dramatically increased the expression of 21 of 23 proteins preferentially found in stalk cells, but drastically repressed 4 major spore-specific… CONTINUE READING