Selective induction of B7/BB-1 on interferon-gamma stimulated monocytes: a potential mechanism for amplification of T cell activation through the CD28 pathway.

Abstract

The B cell activation antigen B7/BB-1 is the natural ligand for the T cell antigen CD28 and these two molecules are capable of mediating T-B cell adhesion. Engagement of the CD28 pathway provides a costimulatory signal to T cells leading to enhanced lymphokine production. We report that interferon-gamma (INF-gamma) induces the expression of B7/BB-1 on… (More)

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Cite this paper

@article{Freedman1991SelectiveIO, title={Selective induction of B7/BB-1 on interferon-gamma stimulated monocytes: a potential mechanism for amplification of T cell activation through the CD28 pathway.}, author={Andrew Freedman and G. J. Freeman and Kurt K Rhynhart and Laura Nadler}, journal={Cellular immunology}, year={1991}, volume={137 2}, pages={429-37} }