Selective induction and subcellular distribution of ACONITASE 3 reveal the importance of cytosolic citrate metabolism during lipid mobilization in Arabidopsis.

@article{Hooks2014SelectiveIA,
  title={Selective induction and subcellular distribution of ACONITASE 3 reveal the importance of cytosolic citrate metabolism during lipid mobilization in Arabidopsis.},
  author={Mark A. Hooks and James William Allwood and Joanna K D Harrison and Joachim Kopka and Alexander Erban and Royston Goodacre and Janneke Balk},
  journal={The Biochemical journal},
  year={2014},
  volume={463 2},
  pages={
          309-17
        }
}
Arabidopsis thaliana has three genes that encode distinct aconitases (ACO), but little is known about the function of each isoenzyme during plant development. In newly emerged seedlings of Arabidopsis, transcript and protein levels for ACO3 were selectively induced to yield more than 80% of total aconitase activity. Characterization of knockout mutants for each of the three ACOs suggests a major role for only ACO3 in citrate metabolism. The aco3 mutant showed delayed early seedling growth… CONTINUE READING
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