Selective increase of the potential anticarcinogen 4-methylsulphinylbutyl glucosinolate in broccoli.

  title={Selective increase of the potential anticarcinogen 4-methylsulphinylbutyl glucosinolate in broccoli.},
  author={Kim K. Faulkner and Richard Mithen and Gary Williamson},
  volume={19 4},
The putative anticarcinogenic activity of Brassica vegetables has been associated with the presence of certain glucosinolates. 4-Methylsulphinylbutyl isothiocyanate (sulphoraphane), derived from the corresponding glucosinolate found in broccoli, has previously been identified as a potent inducer of the anticarcinogenic marker enzyme quinone reductase [NADP(H):quinone-acceptor oxidoreductase] in murine hepatoma Hepa 1c1c7 cells. We have therefore produced a broccoli hybrid with increased levels… CONTINUE READING


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