Selective impairments in dendritic cell-associated function distinguish hepatitis C virus and HIV infection.

@article{Anthony2004SelectiveII,
  title={Selective impairments in dendritic cell-associated function distinguish hepatitis C virus and HIV infection.},
  author={Donald D. Anthony and Nicole L. Yonkers and Anthony Benjamin Post and Robert J Asaad and Frederick P. Heinzel and Michael M. Lederman and Paul Viktor Lehmann and Hern{\'a}n Valdez},
  journal={Journal of immunology},
  year={2004},
  volume={172 8},
  pages={4907-16}
}
Impaired APC functions may play important roles in chronicity of hepatitis C virus (HCV) and HIV infections. To investigate the separate and combined effects of HCV and HIV infection on immature dendritic cells (DCs), we evaluated myeloid-derived DC (MDC) and plasmacytoid-derived DC (PDC) frequencies and functions, measured by Toll-like receptor ligand-induced IFN-alpha and IL-12, in healthy controls and subjects with chronic HCV, HIV, and HCV-HIV infection. To evaluate the relation between… CONTINUE READING

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