Selective impairment of endothelium-dependent relaxations by prostaglandin endoperoxide.

@article{Tesfamariam1994SelectiveIO,
  title={Selective impairment of endothelium-dependent relaxations by prostaglandin endoperoxide.},
  author={Belay Tesfamariam},
  journal={Journal of hypertension},
  year={1994},
  volume={12 1},
  pages={41-7}
}
OBJECTIVE Studies of aortas from hypertensive and diabetic rats and rabbits have demonstrated impairment of endothelium-dependent relaxations, which were associated with increased release of endothelium-derived thromboxane A2 (TXA2). This implicates enhanced release of TXA2 or its precursor prostanoid, prostaglandin endoperoxide (PGH2), or both, as factors… CONTINUE READING