Selective immunoglobulin M deficiency in an adult with Streptococcus pneumoniae sepsis and invasive aspergillosis.

@article{Hong2008SelectiveIM,
  title={Selective immunoglobulin M deficiency in an adult with Streptococcus pneumoniae sepsis and invasive aspergillosis.},
  author={Rong-feng Hong and Sudeep Gupta},
  journal={Journal of investigational allergology & clinical immunology},
  year={2008},
  volume={18 3},
  pages={
          214-8
        }
}
Primary selective immunoglobulin (Ig) M deficiency usually presents early in life with recurrent or severe infections caused by encapsulated and gram-negative organisms. Primary selective IgM deficiency in adults is rare and is usually associated with autoimmune diseases or malignant neoplasm. We performed an extensive immunological analysis of innate and adaptive immunity in an adult patient with possible primary selective IgM deficiency who presented with life-threatening Streptococcus… CONTINUE READING

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