Selective imaging of the angiogenic relevant integrins α5β1 and αvβ3.

Abstract

Pattern seekers: For the two angiogenic relevant integrins α5β1 and αvβ3, functionalized derivatives of the selective antagonists 1 and 2 could target and discriminate between tumor cells in vivo based on their different integrin patterns and also delay tumor growth in vivo. In addition, the first α5β1-selective integrin antagonist that enables specific… (More)
DOI: 10.1002/anie.201306376

Topics

Cite this paper

@article{Neubauer2013SelectiveIO, title={Selective imaging of the angiogenic relevant integrins α5β1 and αvβ3.}, author={Stefanie A Neubauer and Florian Rechenmacher and A. Beer and Flavio Curnis and Karolin Pohle and Calogero D'Alessandria and Hans-J{\"u}rgen Wester and Ute Reuning and Angelo Corti and Markus Schwaiger and Horst Kessler}, journal={Angewandte Chemie}, year={2013}, volume={52 44}, pages={11656-9} }