Selective growth hormone/placental lactogen gene transcription and hormone production in pre- and postmenopausal human ovaries.

@article{Schwaerzler1997SelectiveGH,
  title={Selective growth hormone/placental lactogen gene transcription and hormone production in pre- and postmenopausal human ovaries.},
  author={Peter Schwaerzler and Gerold Untergasser and Martin Hermann and Stephan R Dirnhofer and Burkhard Abendstein and Stephan Madersbacher and Peter Berger},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1997},
  volume={82 10},
  pages={3337-41}
}
In addition to effects of pituitary-derived gonadotropins, human GH modulates and regulates intraovarian reproductive processes in a dose-dependent manner via the endocrine GHRH/GH/insulin-like-growth-factor I (IGF-I) axis. Based on increasing evidence that ovarian regulation involves a complex system of putative para/autocrine factors, we investigated the possibility of gene-selective intraovarian GH/placental lactogen (PL) hormone production, with emphasis on differences between pre- and… CONTINUE READING

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