Selective expression of interleukin-10 gene within glioblastoma multiforme.

  title={Selective expression of interleukin-10 gene within glioblastoma multiforme.},
  author={Takashi G. Nitta and Makoto Hishii and Keisuke Sato and Koji Okumura},
  journal={Brain research},
  volume={649 1-2},
Little information exists regarding which glioma cells are able to escape immune system detection and progress within the host. In order to elucidate some of the mediators which facilitate the growth and spread of glioma cells, the expression of cytokines, TNF-alpha, IL-6, gamma-IFN, IL-10, and GM-CSF, within 12 human glioma specimens was investigated by the polymerase chain reaction. The twelve patients with malignant glioma were categorized into a localized (n = 4) and an invasive glioma (n… CONTINUE READING


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