Selective expansion of a monocyte subset expressing the CD11c dendritic cell marker in the Yaa model of systemic lupus erythematosus.

@article{Amano2005SelectiveEO,
  title={Selective expansion of a monocyte subset expressing the CD11c dendritic cell marker in the Yaa model of systemic lupus erythematosus.},
  author={Hirofumi Amano and Eri Amano and Marie-Laure Santiago-Raber and Thomas Moll and Eduardo Mart{\'i}nez-Soria and Liliane Fossati-Jimack and Masahiro Iwamoto and Stephen J. Rozzo and Brian L. Kotzin and Shozo Izui},
  journal={Arthritis and rheumatism},
  year={2005},
  volume={52 9},
  pages={2790-8}
}
OBJECTIVE Monocytosis is a unique cellular abnormality associated with the Yaa (Y-linked autoimmune acceleration) mutation. The present study was designed to define the cellular mechanism responsible for the development of monocytosis and to characterize the effect of the Yaa mutation on the development of monocyte subsets. METHODS We produced bone marrow chimeras reconstituted with a mixture of Yaa and non-Yaa bone marrow cells bearing distinct Ly-17 alloantigens, and determined whether… CONTINUE READING

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