Selective executive dysfunction but intact risky decision-making in early Huntington's disease.

@article{Holl2013SelectiveED,
  title={Selective executive dysfunction but intact risky decision-making in early Huntington's disease.},
  author={Anna Katharina Holl and Leonora Wilkinson and Sarah J Tabrizi and Annamaria Painold and Marjan Jahanshahi},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2013},
  volume={28 8},
  pages={1104-9}
}
Executive dysfunction, including problems with decision-making, inhibition of prepotent responses, and verbal fluency, are main features of Huntington's disease (HD). The decline of executive function in HD is related to the anatomical progression of HD pathology in the basal ganglia, where the earliest changes of neuronal cell death are seen in the dorsolateral caudate. To examine the specific pattern of executive dysfunction in early HD, 18 patients with early HD were assessed on: (1) the… CONTINUE READING
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