Selective estrogen receptor modulators and cardiovascular events.

  • Kazuo Kitagawa
  • Published 2014 in
    Circulation journal : official journal of the…


ost of the previous observational studies suggest that estrogen replacement therapy reduces cardiovascular risks,1 but meta-analysis of randomized clinical trials showed increased risk of hormone replacement therapy for cardiovascular events.2 Both hypercoagulability and upregulation of inflammation-sensitive proteins could underline the increased risk of estrogen treatment in coronary artery disease (CAD) and ischemic stroke. Article p 135

Cite this paper

@article{Kitagawa2014SelectiveER, title={Selective estrogen receptor modulators and cardiovascular events.}, author={Kazuo Kitagawa}, journal={Circulation journal : official journal of the Japanese Circulation Society}, year={2014}, volume={78 1}, pages={63-4} }