Selective estrogen receptor modulators: tissue actions and potential for CNS protection.

@article{LittletonKearney2002SelectiveER,
  title={Selective estrogen receptor modulators: tissue actions and potential for CNS protection.},
  author={Marguerite T. Littleton-Kearney and Nancy L. Ostrowski and David A. Cox and Mark I. Rossberg and Patricia D. Hurn},
  journal={CNS drug reviews},
  year={2002},
  volume={8 3},
  pages={
          309-30
        }
}
Significant physiologic changes occur during menopause. Evidence exists to suggest that estrogen may be neuroprotective under specific conditions. However, there are limitations in the neuroprotection afforded by standard hormone therapy. Accordingly, alternative agents with selected estrogenic effects may hold even greater promise rather than conventional hormone replacement therapy for the prevention and treatment of CNS injury. Recently, a variety of selective estrogen receptor modulators… 

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