Selective effects of histidine-rich polypeptides on the aggregation and viability of Streptococcus mutans and Streptococcus sanguis.

@article{Payne1991SelectiveEO,
  title={Selective effects of histidine-rich polypeptides on the aggregation and viability of Streptococcus mutans and Streptococcus sanguis.},
  author={Johanna Payne and Vincent J. Iacono and I T Crawford and B M Lepre and E P Bernzweig and B L Grossbard},
  journal={Oral microbiology and immunology},
  year={1991},
  volume={6 3},
  pages={169-76}
}
Enriched preparations of histidine-rich polypeptides (HRPs) and isolated HRP pairs (1-2, 3-4 and 5-6) degrade in the presence of fresh autologous whole saliva to a series of low-molecular-weight cationic peptides (HRPs 6a-c and 7). Analysis of the HRPs during degradation indicates that: HRP 1 is not the parent molecule of the HRPs; the HRP pairs do not convert to each other in a cascade-like sequence in saliva; and the HRPs can be separated into 2 groups consisting of HRPs 1-2 and 3-7… CONTINUE READING