Corpus ID: 9863405

Selective effects of 7 alpha-halogeno substitution on corticosteroid activity: Sch 22219 and Sch 23409.

@article{Lutsky1979SelectiveEO,
  title={Selective effects of 7 alpha-halogeno substitution on corticosteroid activity: Sch 22219 and Sch 23409.},
  author={B. Lutsky and J. Berkenkopf and X. Fern{\'a}ndez and M. Monahan and A. Watnick},
  journal={Arzneimittel-Forschung},
  year={1979},
  volume={29 7},
  pages={
          992-8
        }
}
  • B. Lutsky, J. Berkenkopf, +2 authors A. Watnick
  • Published 1979
  • Chemistry, Medicine
  • Arzneimittel-Forschung
  • Two 7 alpha-halogeno substituted corticosteroids, 7 alpha-chloro-16 alpha-methylprednisolone-17,21 dipropionate (Sch 22219) and 7 alpha-bromo-16 alpha-methylprednisolone-17-benzoate-21-acetate (Sch 23409) were compared to other clinically utilized topical corticosteroids for local and parenteral antiinflammatory and glucocorticosteroid activity. Both compounds were at least equivalent to the most potent comparison corticosteroids in topical antiinflammatory activity, and exhibited favorable… CONTINUE READING
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