Selective editing of Val and Leu methyl groups in high molecular weight protein NMR.

Abstract

The development of methyl-TROSY approaches and specific (13)C-(1)H labeling of Ile, Leu and Val methyl groups in highly deuterated proteins has made it possible to study high molecular weight proteins, either alone or in complexes, using solution nuclear magnetic resonance (NMR) spectroscopy. Here we present 2-dimensional (2D) and 3-dimensional (3D) NMR… (More)
DOI: 10.1007/s10858-012-9629-2

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Cite this paper

@article{Hu2012SelectiveEO, title={Selective editing of Val and Leu methyl groups in high molecular weight protein NMR.}, author={WeiDong Hu and Andrew T. Namanja and Steven Wong and Yuan Chen}, journal={Journal of biomolecular NMR}, year={2012}, volume={53 2}, pages={113-24} }