Selective early cardiolipin peroxidation after traumatic brain injury: an oxidative lipidomics analysis.

@article{Bayir2007SelectiveEC,
  title={Selective early cardiolipin peroxidation after traumatic brain injury: an oxidative lipidomics analysis.},
  author={H{\"u}lya A Bayir and Vladimir A. Tyurin and Yulia Y. Tyurina and Rosa Viner and Vladimir B. Ritov and Andrew A. Amoscato and Qing Zhao and Xiaojing John Zhang and Keri L Janesko-Feldman and Henry Alexander and Liana V. Basova and Robert S B Clark and Patrick M Kochanek and Valerian E Kagan},
  journal={Annals of neurology},
  year={2007},
  volume={62 2},
  pages={154-69}
}
OBJECTIVE Enhanced lipid peroxidation is well established in traumatic brain injury. However, its molecular targets, identity of peroxidized phospholipid species, and their signaling role have not been deciphered. METHODS Using controlled cortical impact as a model of traumatic brain injury, we employed a newly developed oxidative lipidomics approach to qualitatively and quantitatively characterize the lipid peroxidation response. RESULTS Electrospray ionization and matrix-assisted laser… CONTINUE READING
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