Selective digestion of mouse metaphase chromosomes

Metaphase chromosomes prepared from colcemid-treated mouse L929 cells by non-ionic detergent lysis exhibit distinct heterochromatic centromere regions and associated kinetochores when viewed by whole mount electron microscopy. Deoxyribonuclease I treatment of these chromosomes results in the preferential digestion of the chromosomal arms leaving the… (More)

4 Figures & Tables

Topics

Statistics

0100020003000'82'85'89'93'97'01'05'09'13'17
Citations per Year

3,654 Citations

Semantic Scholar estimates that this publication has 3,654 citations based on the available data.

See our FAQ for additional information.