Selective depression of medium-latency leg and foot muscle responses to stretch by an alpha 2-agonist in humans.

@article{Corna1995SelectiveDO,
  title={Selective depression of medium-latency leg and foot muscle responses to stretch by an alpha 2-agonist in humans.},
  author={Stefano Corna and Margherita Grasso and Antonio Nardone and Marco Schieppati},
  journal={The Journal of physiology},
  year={1995},
  volume={484 ( Pt 3)},
  pages={803-9}
}
1. In standing humans, toe-up rotation of a platform induces a short-latency (SLR) and a medium-latency response (MLR) in both soleus (Sol) and flexor digitorum brevis (FDB) muscles. Toe-down rotation evokes a MLR in the tibialis anterior (TA). The SLR is the counterpart of the monosynaptic stretch reflex, but the origin of the MLR is still debated. By means of tizanidine (an alpha 2-adrenergic receptor agonist) we tested the hypothesis that the MLR is relayed by group II afferent fibres, since… CONTINUE READING
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