Selective deficits in the circadian light response in mice lacking PACAP.

@article{Colwell2004SelectiveDI,
  title={Selective deficits in the circadian light response in mice lacking PACAP.},
  author={Christopher S Colwell and Stephan Michel and Jason N Itri and Williams Rodr{\'i}guez and Jimmy C N Tam and Vincent Leli{\`e}vre and Zhou Hu and James A Waschek},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2004},
  volume={287 5},
  pages={
          R1194-201
        }
}
Previous studies indicate that light information reaches the suprachiasmatic nucleus through a subpopulation of retinal ganglion cells that contain both glutamate and pituitary adenylyl cyclase-activating peptide (PACAP). Although the role of glutamate in this pathway has been well studied, the involvement of PACAP and its receptors is only beginning to be understood. To investigate the functions of PACAP in vivo, we developed a mouse model in which the gene coding for PACAP was disrupted by… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 62 CITATIONS, ESTIMATED 51% COVERAGE

Temporally restricted role of retinal PACAP: integration of the phase-advancing light signal to the SCN.

  • Journal of biological rhythms
  • 2009
VIEW 5 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Mice lacking the PACAP type I receptor have impaired photic entrainment and negative masking.

  • American journal of physiology. Regulatory, integrative and comparative physiology
  • 2008
VIEW 8 EXCERPTS
CITES BACKGROUND, RESULTS & METHODS
HIGHLY INFLUENCED

Bladder dysfunction and altered somatic sensitivity in PACAP-/- mice.

  • The Journal of urology
  • 2010
VIEW 2 EXCERPTS
CITES METHODS
HIGHLY INFLUENCED

Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice.

  • Developmental biology
  • 2008
VIEW 5 EXCERPTS
CITES METHODS & BACKGROUND

FILTER CITATIONS BY YEAR

2004
2019

CITATION STATISTICS

  • 12 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 33 REFERENCES

Disrupted circadian rhythms in VIP- and PHI-deficient mice.

  • American journal of physiology. Regulatory, integrative and comparative physiology
  • 2003
VIEW 4 EXCERPTS

Pituitary adenylate cyclase activating peptide phase shifts circadian rhythms in a manner similar to light.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1999
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

The pituitary adenylate cyclase-activating polypeptide modulates glutamatergic calcium sig R1200 PACAP-DEFICIENT MICE AJP-Regul

MD Kopp, H Meissl, F Dehghani, HW. Korf
  • Integr Comp Physiol
  • 2004
VIEW 2 EXCERPTS

Changes in light-induced phase shift of circadian rhythm in mice lacking PACAP.

  • Biochemical and biophysical research communications
  • 2003
VIEW 2 EXCERPTS