Selective deficit in spatial memory strategies contrast to intact response strategies in patients with schizophrenia spectrum disorders tested in a virtual navigation task.

@article{Wilkins2013SelectiveDI,
  title={Selective deficit in spatial memory strategies contrast to intact response strategies in patients with schizophrenia spectrum disorders tested in a virtual navigation task.},
  author={Leanne K Wilkins and Todd A Girard and Kyoko Konishi and Matthew J King and Katherine A Herdman and Jelena P. King and Bruce K. Christensen and Veronique D. Bohbot},
  journal={Hippocampus},
  year={2013},
  volume={23 11},
  pages={1015-24}
}
Spatial memory is impaired among persons with schizophrenia (SCZ). However, different strategies may be used to solve most spatial memory and navigation tasks. This study investigated the hypothesis that participants with schizophrenia-spectrum disorders (SSD) would demonstrate differential impairment during acquisition and retrieval of target locations when using a hippocampal-dependent spatial strategy, but not a response strategy, which is more associated with caudate function. Healthy… CONTINUE READING