Selective cytotoxicity of microcystins LR, LW and LF in rat astrocytes.

Abstract

Microcystins (MCs) comprise a group of cyanobacterial toxins with hepatotoxic, nephrotoxic and, possibly, neurotoxic activity in mammals. In order to understand the development of their neurotoxicity we investigated the toxic effects of MC variants, MC-LR, MC-LW and MC-LF, in astrocytes that play a central role in maintaining brain homeostasis. 24h exposure… (More)
DOI: 10.1016/j.toxlet.2016.11.008

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