Selective cooperation between fatty acid binding proteins and peroxisome proliferator-activated receptors in regulating transcription.

@article{Tan2002SelectiveCB,
  title={Selective cooperation between fatty acid binding proteins and peroxisome proliferator-activated receptors in regulating transcription.},
  author={Nguan-Soon Tan and Natacha S. Shaw and Nicolas Vinckenbosch and Peng Liu and Rubina Yasmin and B{\'e}atrice Desvergne and Walter Wahli and Noa Noy},
  journal={Molecular and cellular biology},
  year={2002},
  volume={22 14},
  pages={
          5114-27
        }
}
Lipophilic compounds such as retinoic acid and long-chain fatty acids regulate gene transcription by activating nuclear receptors such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptors (PPARs). These compounds also bind in cells to members of the family of intracellular lipid binding proteins, which includes cellular retinoic acid-binding proteins (CRABPs) and fatty acid binding proteins (FABPs). We previously reported that CRABP-II enhances the transcriptional… CONTINUE READING

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