Selective changes in EGF receptor expression and function during the proliferation, differentiation and apoptosis of mammary epithelial cells.

Abstract

Epidermal growth factor (EGF) is a multifunctional regulator of mammary epithelial cells (MEC) that transduces its signals through the EGF receptor (EGFR). To clarify the role of the EGFR in the mammary gland, EGFR expression, localization and function were examined during different developmental stages in rats. Immunoblot analysis demonstrated high levels… (More)

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@article{Darcy1999SelectiveCI, title={Selective changes in EGF receptor expression and function during the proliferation, differentiation and apoptosis of mammary epithelial cells.}, author={Kelly Darcy and Ann L. Wohlhueter and D. Zangani and Mary M. Vaughan and J. A. Russell and Patricia A. Masso-Welch and Luis M Varela and Shelby Shoemaker and Elizabeth J. Horn and P. P. Lee and R. Y. Huang and Mary Sau Man Ip}, journal={European journal of cell biology}, year={1999}, volume={78 7}, pages={511-23} }