Selective cell cycle arrest and induction of apoptosis in human prostate cancer cells by a polyphenol-rich extract of Solanum nigrum

@inproceedings{Nawab2011SelectiveCC,
  title={Selective cell cycle arrest and induction of apoptosis in human prostate cancer cells by a polyphenol-rich extract of Solanum nigrum},
  author={Akbar Nawab and Vijay Singh Thakur and Mohammad Amri Mohammad Yunus and Abbas Ali Mahdi and Sanjay Gupta},
  booktitle={International journal of molecular medicine},
  year={2011}
}
Progression of prostate cancer is associated with escape of tumor cells from cell cycle arrest and apoptosis. Agents capable of selectively eliminating cancer cells by cell cycle arrest and/or induction of apoptosis offer a highly desirable approach. Here we demonstrate that a polyphenolic extract derived from ripe berries of Solanum nigrum (SN) differentially causes cell cycle arrest and apoptosis in various human prostate cancer cells without affecting normal prostate epithelial cells… CONTINUE READING

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